For People With Liver Cancer
Treated With Nexavar® (sorafenib) Frequently Asked Questions
Frequently Asked Questions About OPDIVO®
Here are some frequently asked questions and answers that patients like you have had about treatment with OPDIVO. Remember that this information is not a substitute for talking with your healthcare professional. Your healthcare professional is the best source of information about your condition.
What Is OPDIVO?
OPDIVO® (nivolumab) is a prescription medicine used to treat people with liver cancer (hepatocellular carcinoma) after you have received treatment with Nexavar® (sorafenib). OPDIVO was approved based on response rate and how long patients’ responses lasted. There is ongoing evaluation of clinical benefit of OPDIVO for this use.
It is not known if OPDIVO is safe and effective in children less than 18 years of age.
HOW IS OPDIVO DIFFERENT FROM CHEMOTHERAPY?
OPDIVO is different from oral targeted therapies and traditional chemotherapy for people with advanced HCC who have been previously treated with Nexavar®. OPDIVO is an immunotherapy treatment. It’s a type of medicine that works with your immune system.
DO I NEED TO TAKE A TREATMENT IN ADDITION TO OPDIVO FOR IT TO WORK?
OPDIVO is a monotherapy, that is, a medication that is taken alone rather than in combination with other treatments, such as radiation or chemotherapy.
HOW WILL I RECEIVE OPDIVO?
Your healthcare provider will give you OPDIVO into your vein through an intravenous (IV) line over 30 minutes. OPDIVO is usually given every 2 weeks or 4 weeks depending on the dose you are receiving. Your healthcare provider will decide how many treatments you need. Your healthcare provider will do blood tests to check you for side effects during treatment with OPDIVO and may treat you with a corticosteroid or hormone replacement medicines. OPDIVO treatments may also need to be delayed or completely stopped if you have severe side effects. If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment. Be sure to talk to your healthcare team about side effects.
Where can I go to get my OPDIVO treatments?
You and your doctor should discuss the best place to get your infusions, whether it’s your doctor’s office, an infusion center, or a local hospital.
How do I know if I'm responding to OPDIVO?
While undergoing treatment with OPDIVO, your doctor will likely order periodic scans to evaluate whether there are any changes in the size of your tumors.
What should I know about potential side effects?
Although they may not be experienced by every patients OPDIVO can cause serious side effects. OPDIVO can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become serious or life-threatening and can lead to death. These problems may happen anytime during treatment or even after your treatment has ended.
What are the most common side effects of OPDIVO?
The most common side effects of OPDIVO include:
- feeling tired
- pain in muscles, bones, and joints
- shortness of breath
- decreased appetite
- upper respiratory tract infection
- itchy skin
- back pain
- stomach pain
What are the serious side effects of OPDIVO?
A side effect is described as “serious” if it can sometimes become life-threatening and can lead to death. They can happen anytime during treatment or even after your treatment has ended.
- lung problems (pneumonitis)
- intestinal problems (colitis) that can lead to tears or holes in your intestine
- liver problems (hepatitis)
- hormone gland problems (especially the thyroid, pituitary, adrenal glands, and pancreas)
- kidney problems, including nephritis and kidney failure
- skin problems
- inflammation of the brain (encephalitis)
- problems in other organs
- severe infusion reactions
Who can I talk to if I need help or have questions about OPDIVO?
Talk with your healthcare professional first if you have questions about this treatment option. You can also call a Care Navigator at 1-855-673-4861,
8 AM to 8 PM ET, Monday to Friday, for general questions about OPDIVO not specific to your health.
It can be helpful to review a list of questions you may want to ask your doctor. Download Questions to Ask Your Doctor to help answer your questions about whether OPDIVO may be right for you.
See Clinical Trial Results
See how OPDIVO performed in a clinical trial in patients.See the Results
Complimentary support, tools, and educational resources
for anyone considering or currently taking OPDIVO. Call 1-855-OPDIVO-1 or click to learn more.
Talking With Your Doctor Is Key
Review a list of questions with your oncologist about whether OPDIVO is right for you.Talk to Your Doctor